Magnolia Flower Reduces Tumors
Magnolia officinalis, a beautiful Spring Flower Fights Cancer in Multiple Ways
Isaac Eliaz, M.D., founder and medical director of the Amitabha Medical Clinic in Santa Rosa, California. Stated: "The results have been nothing short of remarkable. It is one of the single most powerful natural anti-cancer agents. It is a very exciting compound when it comes to cancer therapy."
Mitchell L Gaynor, M.D., recently deceased, was a board certified medical oncologist and pioneer in integrative oncology who also used the magnolia extract for years to treat cancer and to prevent cancer from becoming active. Dr. Gaynor said it "has a wide range of applications that target the specific mechanisms cancer cells employ in order to grow and spread inside the body."
Another Doctor, Dr. David Williams, a leading authority on natural healing, says, "...the amount and variety of beneficial activity stemming from this one compound isstaggering, particularly when it comes to treating cancer."
Chinese Medicine and Magnolia
For centuries the Chinese therapists have used the bark, cones and leaves of the species Magnolia officinalis, which they called houpa, to treat a wide variety of ailments including anxiety, inflammation, cough, digestive disorders and allergic diseases.
Magnolia Effective for Brain Cancers
Very few remedies can cross the blood-brain barrier (BBB) and therefore brain cancer is a challenge to treat. Many natural agents as well as chemotherapy cannot enter the brain.
Scientists at the West China Medical School found that the Magnolica inhibits the growth of brain tumors (gliosarcoma) and therefore concluded that it indeed does cross the brain barrier.
Kills cancer cells directly
A study published in the medical journal Cancer in 2012 looked at the effect of Magnolia in a bone cancer (osteosarcoma) mouse model. After seven days after injecting the remedy, the spread of micrometastases (tumors less than 2 millimeters) in the lung was reduced by 41% and the number of macrometastases (greater than 2 millimeters) was reduced by 69% in the lung and 80% in the liver.
Magnolia (Honokiol ) caused rapid cell death in osteosarcoma cell cultures.The Medical researchers concluded that "Magnolia (honokiol) has considerable potential for the treatment of metastasizing osteosarcoma."
Normal cells only live a certain programmed period of time and then they die and are replaced by new cells. Cancer cells are almost ‘immortal’ as this normal feature of programmed cell death (apoptosis) fails. Unlike many remedies that target a single pathway to induce apoptosis, Magnolia achieves this through multiple pathways, including the two principle ones called the death receptor pathway and the mitochondrial pathway.
After doing laboratory studies with pure Magnolia in both animals and test tube cultures it demonstrated apoptosis in cancers of the liver, lung, breast, colon, prostate, pancreas and chronic lymphocytic leukemia. And Magnolia was also found to be "highly effective in inhibiting melanoma cancer cells...."
Cancer cells are hard to destroy because they use a process called angiogenesis. This means that the cancer cells are able to build their own blood supply by forming their own network of blood vessels to supply oxygen and nutrients. This allows cancer to grow and eventually spread.
The really good news is that 100% pure Magnolia Essential oil has been shown to achieve this by suppressing the over activity of nuclear factor-kappaB (NF-kB), a protein that supports cell growth.
Magnolia (Honokiol ) has also been found to inhibit one of the main pathways involved with tumor growth, called vascular endothelial growth factor (VEGF).
But that is not all; another factor that plays an important role in angiogenesis is STAT3. And once again Magnolia was found to act on this gene's pathway to inhibit the spread of gastric cancer in mice.
Other Important Influences
Magnolia Honokiol has been shown to prevent signaling in tumors with faulty p53. The tumor suppressor gene known as p53 is important in ensuring correct DNA replication, preventing mutations and regulating the cell cycle. It plays a role in both apoptosis and anti-angiogenesis. A defective p53 gene can cause mutations, thereby increasing the risk of cancers and making them more aggressive and resistant to treatment.
Magnolia prevents Ras (a family of genes that, when mutated, stimulates growth in about one in three cancers) from switching on phospholipase D, an enzyme that allows cancer cells to stay alive when they would ordinarily die according to Jack Arbiser is an M.D., Ph.D., and professor of dermatology at Emory University School of Medicine, Atlanta, Georgia
Magnolia has been shown to bind strongly to EGFR, blocking its actions. EGFR: Epidermal Growth Factor Receptor is a protein that is overabundant in many cancers and in virtually all head and neck cancers. In this respect Magnolia outperformed, both in cell lines and mice, a drug commonly used to treat head and neck cancers.
Boosts conventional and natural treatments
If you are already receiving chemotherapy, Magnolia can safely be used along with chemotherapy and appears to improve patient outcomes. It enhanced the chemotherapy drug gemcitabine against pancreatic cancer. It boosted the cytotoxic drug cisplatin against colon and ovarian cancer. It worked synergistically with imatinib against human leukemia cells. It also enhanced the potency of three drugs in B-cell chronic lymphocytic leukemia cells.
Radiation and chemotherapy drugs sometimes lose any effectiveness they may possess because cancer cells become desensitized and resistant to them. Magnolia has been shown to resensitize tumors to an antibiotic used in uterine cancer. It has also been effective in radiation therapy, sensitizing treatment-resistant colon cancer stem cells.
Many people who suffer from cancer and other chronic illnesses also have problems with inflammation. Magnolia (Honokiol) also has strong anti-inflammatory activity and is a powerful natural antioxidant.
With all the research done up to now the Magnolia (honokiol ) appears to be a safe compound. The only direct toxicological study performed on rats also found it to be safe.
Dosage: Take 4 - 6 drops under the tongue with any meal twice a day and hold for 30 seconds and then swallow. Total of 8 to 12 drops per day.